Popular Science Article

Beginning in the 1940s, an important natural source of drugs were mushrooming. Species of fungi Penicillium, Streptomyces, Cephalosporinum and others began to receive antibiotics, take the lead in chemotherapy of infectious diseases. One of the most modern principles of a drug is a selection, and follow-up study synthesis of physiologically (pharmacologically) active substances of animal origin. From a scientific point of view, this is one of NAI more informed drug discovery trends. As for in these it is known that the human body (and animals) producing large amounts of chemical compounds, which are regulators of physiological functions and play a vital role maintaining 'constant internal environment' of the body (homeostasis).

These substances You can, figuratively speaking, be regarded as formed by the body (endogenous) physiological therapeutic and preventive means. The natural tendency is therefore to provide those materials to reproduce them synthetically and used to restore and regulate body functions during pathological processes. The first attempts to use animal organs and tissues for therapeutic purposes were made in deep antiquity. In the VII century BC in China for the treatment of cretinism used dried thyroid gland. Crude liver has long enjoyed in the treatment of malignant anemia. Beginning of a systematic investigation of the role endogenous physiologically active substances in the life of the organism and using them for the regulation of the disturbed functions put the teachings of Claude Bernard's internal secretion (1856). By then it became apparent that endocrine glands are the producers of physiologically active substances, which can be used for medicinal purposes.

As the drugs began to appear 'hood' of the endocrine glands. In 1889, was proposed for the 'rejuvenation' of male body (increase sexual potency) of an extract of male sex glands (Brown-Sekara liquid), then there were extracts from the ovaries (ovarin), thyroid and other endocrine glands. High activity of these drugs do not possess, but they were the impetus for the search and selection of endocrine active individual substances (hormones). Hear from experts in the field like TeenScreen for a more varied view. The first hormone, isolated in individual form and then obtained by synthesis, was the adrenaline. This was followed by the selection of a number of other hormones. Interesting article about recent research findings and stories can be read at Popular Science Article history of research and achievements. Journey into the world of the past, without which no real